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Jan Delabie, Professor MD, PhD.

Consultant histopathologist
Professor
Hematopathology
Division of Pathology
Rikshospitalet
0027 Oslo
Norway

Office: + (47) 2293
Fax: + (47)
email: jan.delabie@radiumhospitalet.no


Training:

Expertise:
Hematopathology

Research Interests:
Hematopathology research, both basic, applied and clinical research

Professional Service:

Other Links:


Selected Publications:

Lenz G, Davis RE, Ngo VN, Lam L, George TC, Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI, Chan WC, Staudt LM.
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma.
Science. 2008 Mar 21;319(5870):1676-9. Epub 2008 Mar 6.

Pike BL, Greiner TC, Wang X, Weisenburger DD, Hsu YH, Renaud G, Wolfsberg TG, Kim M, Weisenberger DJ, Siegmund KD, Ye W, Groshen S, Mehrian-Shai R, Delabie J, Chan WC, Laird PW, Hacia JG.
DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status.
Leukemia. 2008 Feb 21; [Epub ahead of print]

Young KH, Weisenburger DD, Dave BJ, Smith L, Sanger W, Iqbal J, Campo E, Delabie J, Gascoyne RD, Ott G, Rimsza L, Müller-Hermelink HK, Jaffe ES, Rosenwald A, Staudt LM, Chan WC, Greiner TC.
Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma.
Blood. 2007 Dec 15;110(13):4396-405. Epub 2007 Sep 19.

Kimm LR, deLeeuw RJ, Savage KJ, Rosenwald A, Campo E, Delabie J, Ott G, Muller-Hermelink HK, Jaffe ES, Rimsza LM, Weisenburger DD, Chan WC, Staudt LM, Connors JM, Gascoyne RD, Lam WL.
Frequent occurrence of deletions in primary mediastinal B-cell lymphoma.
Genes Chromosomes Cancer. 2007 Dec;46(12):1090-7.

Iqbal J, Greiner TC, Patel K, Dave BJ, Smith L, Ji J, Wright G, Sanger WG, Pickering DL, Jain S, Horsman DE, Shen Y, Fu K, Weisenburger DD, Hans CP, Campo E, Gascoyne RD, Rosenwald A, Jaffe ES, Delabie J, Rimsza L, Ott G, Müller-Hermelink HK, Connors JM, Vose JM, McKeithan T, Staudt LM, Chan WC;
Leukemia/Lymphoma Molecular Profiling Project.Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma.
Leukemia. 2007 Nov;21(11):2332-43. Epub 2007 Jul 12.

Ikonomou IM, Aamot HV, Heim S, Fosså A, Delabie J.
Granulomatous slack skin with a translocation t(3;9)(q12;p24).
Am J Surg Pathol. 2007 May;31(5):803-6.

Kolstad A, Nome O, Delabie J, Lauritzsen GF, Fossa A, Holte H.
Standard CHOP-21 as first line therapy for elderly patients with Hodgkin’s lymphoma.
Leuk Lymphoma. 2007 Mar;48(3):570-6.

Micci F, Panagopoulos I, Tjønnfjord GE, Kolstad A, Delabie J, Beiske K, Heim S.
Molecular cytogenetic characterization of t(14;19)(q32;p13), a new recurrent translocation in B cell malignancies.
Virchows Arch. 2007 May;450(5):559-65. Epub 2007 Apr 4.

Wiestner A, Tehrani M, Chiorazzi M, Wright G, Gibellini F, Nakayama K, ‘
Liu H, Rosenwald A, Muller-Hermelink HK, Ott G, Chan WC, Greiner TC, Weisenburger DD, Vose J, Armitage JO, Gascoyne RD, Connors JM, Campo E, Montserrat E, Bosch F, Smeland EB, Kvaloy S, Holte H, Delabie J, Fisher RI, Grogan TM, Miller TP, Wilson WH, Jaffe ES, Staudt LM.
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival.
Blood. 2007 Jun 1;109(11):4599-606. Epub 2007 Feb 13.

Salaverria I, Zettl A, Beà S, Moreno V, Valls J, Hartmann E, Ott G, Wright G, Lopez-Guillermo A, Chan WC, Weisenburger DD, Gascoyne RD, Grogan TM, Delabie J, Jaffe ES, Montserrat E, Muller-Hermelink HK, Staudt LM, Rosenwald A, Campo E.
Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature.
J Clin Oncol. 2007 Apr 1;25(10):1216-22. Epub 2007 Feb 12.

Davies AJ, Rosenwald A, Wright G, Lee A, Last KW, Weisenburger DD, Chan WC, Delabie J, Braziel RM, Campo E, Gascoyne RD, Jaffe ES, Muller-Hermelink K, Ott G, Calaminici M, Norton AJ, Goff LK, Fitzgibbon J, Staudt LM, Andrew Lister T.
Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms.
Br J Haematol. 2007 Jan;136(2):286-93.